Cell Membrane-Virus Interaction

Code for the paper FIB-SEM as a Volume Electron Microscopy Approach to Study Cellular Architectures in SARS-CoV-2 and Other Viral Infections: A Practical Primer for a Virologist.

Requirements

The following python packages need to be installed before running the script (with pip or conda):

• numpy
• scipy
• trimesh
• pandas
• open3d
• seaborn

Raw Data

Available shortly from EMPIAR-10677.

Running the Code

Example data is provided in the membrane_curvature directory. To run the script:

python surface_curvature.py data_config.yaml

All parameters needed for measurement, including filenames, are encapsulated in the .yaml config file. The yaml file contains detailed notes describing each parameter.