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Structural and Functional Connectivity of the Salience Network in Subjective Cognitive Decline

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SC-FC

Structural and Functional Connectivity Project

Aim

Compute ROI-to-ROI functional connectivity of the salience/cingulo-opercular network for correlation with structural connectivity of this network in healthy older adults (with and without subjective cognitive decline).

Scripts

  • Looping BASH scripts to apply FSL functions (v.6.0.1) across participants to obtain ROIs' time courses.

  • The ROI-to-ROI functional connectivity was computed in R (see the corresponding R scripts).

  • The script numbering reflects the order of analysis steps followed.

ROI selection

  • ROIs were obtained and selected from the 360-area MNI map derived from the multimodal parcellation of Glasser et al. (2016).

  • ROIs were visually inspected to overlap with the anterior salience network map of Shirer et al. (2012).

  • ROI time course extraction was run on Ubuntu 16.04.5 LTS (Xenial Xerus) with FSL v.6.0.1.

Report

  • Theory, method description, and results can be found here.

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Structural and Functional Connectivity of the Salience Network in Subjective Cognitive Decline

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